Prostate cancer prevention trial launched
نویسندگان
چکیده
منابع مشابه
High-grade prostate cancer and the prostate cancer prevention trial.
Prostate cancer remains a major public health challenge worldwide and has defied efforts to develop effective and acceptable therapy for its control. This reality provides a strong rationale for focusing on prevention. In the Prostate Cancer Prevention Trial (PCPT), the 5α-reductase inhibitor finasteride reduced the prevalence of prostate cancer by 24.8% (versus placebo) in 18,882 men randomize...
متن کاملFinasteride and high-grade prostate cancer in the Prostate Cancer Prevention Trial.
BACKGROUND The Prostate Cancer Prevention Trial (PCPT) reported a decreased incidence of prostate cancer overall but an increase in the incidence of high-grade prostate cancer with finasteride compared with placebo. We assessed whether the increased high-grade prostate cancer associated with finasteride in the PCPT was due to finasteride's potential effects on tumor morphology or prostate size....
متن کاملAssociation of symptomatic benign prostatic hyperplasia and prostate cancer: results from the prostate cancer prevention trial.
This study examined the association between symptomatic benign prostatic hyperplasia (BPH) and prostate cancer risk in 5,068 placebo-arm participants enrolled in the Prostate Cancer Prevention Trial (1993-2003). These data include 1,225 men whose cancer was detected during the 7-year trial--556 detected for cause (following abnormal prostate-specific antigen or digital rectal examination) and 6...
متن کاملDiet, supplement use, and prostate cancer risk: results from the prostate cancer prevention trial.
The authors examined nutritional risk factors for prostate cancer among 9,559 participants in the Prostate Cancer Prevention Trial (United States and Canada, 1994-2003). The presence or absence of cancer was determined by prostate biopsy, which was recommended during the trial because of an elevated prostate-specific antigen level or an abnormal digital rectal examination and was offered to all...
متن کاملAssessing prostate cancer risk: results from the Prostate Cancer Prevention Trial.
BACKGROUND Prostate-specific antigen (PSA) testing is the primary method used to diagnose prostate cancer in the United States. Methods to integrate other risk factors associated with prostate cancer into individualized risk prediction are needed. We used prostate biopsy data from men who participated in the Prostate Cancer Prevention Trial (PCPT) to develop a predictive model of prostate cance...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Medicine
سال: 2001
ISSN: 1078-8956,1546-170X
DOI: 10.1038/nm1001-1076b